Syrup Preparation System

Our Syrup Preparation System normally has heating and heat preservation functions, and is manufactured, pressure tested and accepted in accordance with the "Technical Conditions for Steel Welded Containers".

② The volume is available in various specifications from 100L to 7000L for your selection, and can also be designed and processed according to the actual needs of customers.

③ The seal of the stirring shaft adopts imported sanitary mechanical seals and leak-proof devices. The reducer uses German Flanders or SEW, and the stirring speed is 36-53 rpm. It can also be controlled by a frequency converter.

④ The interface adopts the universal ISO standard quick-release chuck type, and the inner tank uses imported 316L or 304.

⑤ The tank body has a liquid level gauge (contactless ultrasonic, static pressure transmitter or glass tube type), an air respirator, a sterilization steam port, a thermometer (digital display or dial type), a CIP universal tank washer, a lamp hole sight glass, several liquid inlets and outlets, and a manhole.

Configuration:

• Speed reducer (Flender or SEW, Germany)

• Folded microporous membrane air filter (filters ≥0.01μm bacteria)

• Liquid level gauge interface (static pressure sensor, ultrasonic, glass tube position measurement for selection)

• Thermometer and flow meter interface (temperature sensor, flow valve)

• Exhaust and safety valve interface (connect to a respirator with sterile filtration)

• Steam sterilization filtration sterile ventilation interface

• Cleaning ball interface (360 degree rotation under low pressure)

• Medicine liquid inlet and outlet (quick-install type)

• Elliptical manhole

• Sight glass

• Light hole

Main Parts specification

• Internal shape: vertical barrel (inner cylinder in contact with liquid medicine)

• Internal material: 316L (imported)

• Internal finish: 0.28～0.45μm

• Exterior material: 304 mirror plate or matte plate

• Heating coil: 304

• Insulation material: pearl cotton (high temperature resistant, anti-aging)

• Exterior temperature: ≤10℃

• Working pressure: normal pressure

• Working temperature: 60℃～100℃

• Sterilization pressure: 0.15～0.3Mpa

• Sterilization temperature: 121℃～132℃

1. Strict GMP Compliance
The system is fully designed and manufactured in accordance with GMP standards. All components in direct contact with oral liquid—including tank bodies, pipelines, valves, and stirrers—are constructed from 316L stainless steel, a material that is non-toxic, corrosion-resistant, and non-reactive with pharmaceutical ingredients. Internal surfaces in contact with materials undergo electrolytic polishing to achieve a roughness of Ra≤0.4μm, while external surfaces are mechanically polished to Ra≤0.8μm, eliminating sanitary dead angles. Welding processes are rigorously controlled: 20% of automatic welds and 100% of manual welds undergo endoscope inspection, ensuring pipeline integrity and cleanliness to meet pharmaceutical regulatory requirements.

2. Efficient and Precise Performance
The system delivers reliable performance for critical production steps. It features jacketed preparation tanks capable of efficient heating and cooling, with precise temperature control accuracy of ±2℃ to ensure stable material dissolution and reaction conditions. Stirring systems use 316L stainless steel frame-type agitators with variable speed control, ensuring uniform mixing of materials. Integrated weighing systems with high-precision sensors enable accurate batching, while sanitary filters (equipped with appropriate cartridges) effectively remove impurities, ensuring the clarity and purity of oral liquid products.

3. Advanced Automated Control
Equipped with a Siemens PLC and color touchscreen control system, the system enables fully automatic operations, including batching, mixing, online cleaning (CIP), and online sterilization (SIP). It supports recipe management, allowing storage and recall of multiple production formulas, and provides real-time monitoring of key parameters such as temperature, pressure, and stirring speed. The system includes robust audit trail functionality to record user logins, parameter modifications, and alarm events, along with multi-level user permissions (operator, supervisor, administrator) to prevent unauthorized access, ensuring process traceability and data integrity.

4. Hygienic Design and Easy Maintenance
Hygiene is prioritized through thoughtful design elements, including 360° sanitary spray balls for comprehensive tank cleaning, dead-angle-free diaphragm valves to prevent material residue, and hydrophobic breathers with heating jackets to avoid condensation and contamination. Quick-opening manholes, standardized quick-clamp connections, and detachable components facilitate easy disassembly for cleaning and sterilization. Welds and pipelines are designed for durability and ease of inspection, while clear technical documentation (including maintenance manuals) simplifies routine upkeep, calibration, and troubleshooting.

5. Comprehensive After-Sales Support
The manufacturer provides extensive after-sales services to ensure reliable operation. This includes factory and on-site acceptance testing (FAT/SAT), assistance with installation qualification (IQ) and operational qualification (OQ) to meet regulatory requirements, and on-site installation within a specified timeframe. Operator training is offered to ensure proficiency in system operation, maintenance, and fault diagnosis. A warranty period covers manufacturing defects, with prompt technical support and free replacement of faulty parts, minimizing production downtime and supporting continuous, stable production.